Table 2 SNP information

From: Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia

Gene

SNP

Location

Minor/major allele

Minor allele frequency in cases

Minor allele frequency in controls

X2

P-value

OR for minor allele

PGC risk allele

PGC 2014 odds ratio

MIR137HG

rs1625579

Intronic

G/T

0.163

0.178

0.1705

0.679

0.899

T

1.120

miR-137-regulated gene risk score SNPs

 TCF4

rs2276195

Intronic

T/C

0.163

0.296

10.18

0.001

0.464

T

0.990

 PTGS2

rs10489401

Upstream

G/A

0.287

0.398

5.758

0.016

0.608

A

1.005

 MAPK1

rs9610608

Upstream

G/A

0.191

0.102

7.037

0.008

2.073

A

0.995

 MAPK3

rs7202714

Upstream

T/C

0.393

0.265

8.062

0.004

1.796

T

1.039

  1. Abbreviations: OR, odds ratio; PGC, psychiatric genomics consortium; SNP, single-nucleotide polymorphism.
  2. Table shows information for all SNPs used in this study. All risk score SNPs were found to have significantly different minor allele frequencies between cases and controls. All SNPs are within 110 kb upstream to 40 kb downstream of each gene’s boundary.
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