Table 3 Brain regions in the spatial pattern that showed genetic and diagnostic interactive effects
Spatial weighting | Area | L/R Brodmann area | L/R volume (cm3) | L/R max Z-score region and coordinates (x, y, z) |
|---|---|---|---|---|
Positively weighted | Inferior occipital gyrus/inferior parietal lobule | 19/40 | 0.8/0.6 | 6.4 (−38, −68, 2)/5.2 (36, −41, 37) |
Angular gyrus | 39/39 | 0.4/0.8 | 6.3 (−40, −55, 29)/5.9 (44, −55, 27) | |
Middle occipital gyrus | 19/NA | 1.0/0.0 | 5.8 (−40, −70, 5)/NA | |
Occipital gyrus/inferior temporal gyrus | 19/47 | 0.4/0.3 | 5.8 (−42, −70, 2)/4.7 (42, −66, 2) | |
Angular gyrus/inferior parietal lobule | 39/40 | 0.4/1.5 | 5.3 (−40, −51, 27)/5.7 (40, −41, 37) | |
Angular gyrus | 39/39 | 0.3/0.5 | 4.7 (−40, −55, 32)/5.4 (44, −57, 30) | |
Inferior parietal lobule, supramarginal gyrus | NA/40 | 0.0/1.3 | NA/5.3 (44, −43, 39) | |
Middle temporal gyrus | 39/39 | 0.3/0.3 | 5.1 (−40, −59, 29)/4.6 (46, −57, 23) | |
Fusiform gyrus | 19/NA | 0.1/0.0 | 4.3 (−40, −70, −5)/NA | |
Superior parietal lobule | 7/7 | 0.1/0.4 | 3.8 (−34, −65, 51)/4.3 (32, −67, 49) | |
Calcarine/lingual gyrus | 18/18 | 0.2/0.1 | 3.8 (−6, −95, −5)/3.6 (20, −82, −1) | |
Negatively weighted | Middle occipital gyrus | 18/NA | 0.7/0.0 | 5.8 (−30, −77, 13)/NA |
Middle temporal gyrus | 37/NA | 0.8/0.0 | 5.7 (−44, −56, 5)/NA | |
Cuneus | 23/48 | 1.0/0.6 | 4.9 (−18, −55, 25)/4.4 (34, 15, 29) | |
Middle frontal gyrus | NA/48 | 0.0/0.4 | NA/4.1 (30, 27, 26) | |
Inferior temporal gyrus | 20/NA | 0.3/0.0 | 4.1 (−46, −23, −24)/NA | |
Precuneus | 23/NA | 0.1/0.0 | 3.9 (−14, −52, 17)/NA | |
Lingual gyrus | 18/18 | 0.1/0.1 | 3.8 (−18, −72, 2)/3.8 (16, −70, 3) |
