Table 2 WM clusters associating with heroin use

From: Diffusivity of the uncinate fasciculus in heroin users relates to their levels of anxiety

Tracts/Regions

 

Laterality

Coordinate

No. of voxels

t-value

Negative association

 FA

SLF

L

−26, −1, 31

2172

4.68

 

CST

L

−4, −29, −33

425

4.63

 

CST/ATR

L

−10, −28, −18

318

5.08

 

ILF/IFOF/SLFt/SLF

L

−35, −39, 11

242

4.52

Positive association

 MD

IFOF/ATR/UF

L

−30, 46, −2

168

5.13

 RD

ILF/IFOF/SLFt/SLF

L

−35, −39, 11

5017

6.57

 

IFOF/ATR/UF

L

−30, 46, −2

446

5.14

 

FMA

L

−11, −41, 19

184

4.18

 

ATR

L

−24, −49, 29

64

2.87

 

ILF

L

−22, −53, 31

57

3.25

 

SLF/SLFt

L

−31, −6, 17

16

5

  1. Abbreviations: ATR, anterior thalamic radiation; CST, corticospinal tract; FA, fractional anisotropy; FMA, forceps major; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; L, left; MD, mean diffusivity; R, right; SLF, superior longitudinal fasciculus; SLFt, temporal division of the superior longitudinal fasciculus; UF, uncinate fasciculus; WM, white matter.
  2. Peak voxel of each WM cluster is shown. Age and Raven’s Progressive Matrices score were included as covariates using a statistical threshold of P<0.05 after family-wise error correction. The coordinates were in Montreal Neurological Institute (MNI) space.