Table 3 Multiple linear regression analyses of TOI-predicting HADS scores

From: Diffusivity of the uncinate fasciculus in heroin users relates to their levels of anxiety

Dependent variable

Independent variable

   

bDiffusivity indices of TO I

r2

HADS-anxiety

 

FA

FMA

−41.803

0.1114

  

L ATR

19.656

0.1055

  

L CST

22.284

0.1063

  

L IFOF

−18.367

0.1046

  

L ILF

−7.432

0.1037

  

L SLF

−122.211

0.1403

  

L SLFt

−90.204

0.1327

  

L UF

−8.737

0.1037

 

MD

FMA

−58 062.589

0.2195

  

L ATR

50 499.575

0.2311

  

L CST

−4269.317

0.1083

  

L IFOF

1144.624

0.1035

  

L ILF

−61 504.241

0.1805

  

L SLF

−1770.156

0.1036

  

L SLFt

1090.807

0.1035

  

L UF

77 909.239*

0.3049

HADS-depression

 

FA

FMA

−19.276

0.1904

  

L ATR

−17.440

0.1901

  

L CST

22.581

0.1939

  

L IFOF

−14.795

0.1876

  

L ILF

3.361

0.1855

  

L SLF

11.759

0.1865

  

L SLFt

17.889

0.1889

  

L UF

−26.756

0.1917

 

MD

FMA

9305.729

0.1943

  

L ATR

13 905.994

0.2141

  

L CST

4041.296

0.1981

  

L IFOF

4091.053

0.1861

  

L ILF

−1382.170

0.1856

  

L SLF

7837.844

0.1912

  

L SLFt

1212.168

0.1855

  

L UF

8620.549

0.1928

  1. Abbreviations: ATR, anterior thalamic radiation; CST, cerebrospinal tract; FA, fractional anisotropy; FMA, forceps major; HADS, Hospital Anxiety and Depression Scale; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; L, left; MD, mean diffusivity; R, right; SLF, superior longitudinal fasciculus; SLFt, temporal division of the superior longitudinal fasciculus; TOI, tract of interest; UF, uncinate fasciculus.
  2. The b (the unstandardized coefficients) and r2 values (portion of variance explained) from multiple linear regression analyses of FA and the MD of TOIs for predicting the HADS anxiety and depression scores in heroin users are presented after controlling for age, Raven’s Progressive Matrices score and abstinence.
  3. *P<0.05.
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