Table 1 Demographics, clinical variables and facial affect recognition performance for healthy male volunteers and cocaine-dependent men

From: In the face of threat: neural and endocrine correlates of impaired facial emotion recognition in cocaine dependence

Descriptive variables

Control group (N=29)

Cocaine group (N=29)

Group comparison

 

Mean

s.d.

Mean

s.d.

t or F

P

Age (years)

36.8

±10.1

35.5

±8.7

0.53

0.599

Verbal IQ (NART score)

115.2

±5.9

104.1

±9.9

5.12

<0.001

Serum testosterone (nmol/L)a

15.4

±5.0

11.8

±5.1

2.70

0.009

Serum cortisol (nmol/L)a

282.3

±96.8

316.3

±146.0

−1.03

0.306

Testosterone–cortisol ratio

0.07

±0.04

0.04

±0.03

2.40

0.020

Dysphoric mood (BDI-II score)

3.3

±4.1

19.8

±12.0

−7.01

<0.001

State anxiety (STAI score)

28.8

±6.8

39.8

±14.4

−3.69

0.001

Trait anxiety (STAI score)

32.0

±8.5

47.2

±12.7

−5.29

<0.001

Facial identity recognition (performance score)

 Benton test

23.1

±1.9

22.6

±2.0

1.00

0.324

Facial expression recognition accuracy (% correct responses)

 Happy

97.8

±6.4

96.4

±7.5

0.57

0.455

 Surprise

88.3

±13.3

87.9

±12.6

0.01

0.920

 Fear

77.4

±15.5

60.9

±20.1

12.33

0.001

 Sad

93.4

±12.3

89.1

±17.3

1.20

0.279

 Disgust

72.9

±29.6

61.0

±32.8

2.10

0.152

 Anger

80.0

±18.8

66.0

±24.2

6.03

0.017

Facial expression recognition latency (mean response time in seconds)

 Happy

1.45

±0.30

1.54

±0.61

0.55

0.462

 Surprise

1.80

±0.51

2.03

±0.67

2.13

0.150

 Fear

2.16

±0.84

2.29

±0.52

0.48

0.491

 Sad

1.72

±0.49

1.91

±0.77

1.25

0.268

 Disgust

1.97

±1.08

2.21

±1.09

0.73

0.398

 Anger

2.14

±0.63

2.32

±0.66

1.13

0.292

  1. Abbreviations: BDI-II, Beck Depression Inventory; NART, National Adult Reading Test; STAI, State–Trait Anxiety Inventory.
  2. aReference ranges provided by the laboratory: testosterone 8–29 nmo/L and cortisol 280–650 nmol/L.