Table 1 Upregulated genes in stressed rat amygdala

From: Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD

Gene

Names of genes listed in gene cards

Fold changes

Significance

  

Stress/Con

Log(2)

P-value

FDR

Akap1

A kinase anchor protein 1

2.39

1.25

0.0098

0.0155

Arntl2

Aryl hydrocarbon receptor nuclear translocator-like 2

7.86

2.97

0.0001

0.0028

Atp5c1

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 11

2.36

1.24

0.0111

0.0165

Atp5f1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1

3.02

1.59

0.0002

0.0029

Camk2g

calcium/calmodulin-dependent protein kinase II gamma

4.13

2.05

0.0032

0.0086

Cox8a

cytochrome c oxidase subunit VIIIA (ubiquitous)

2.61

1.38

0.0024

0.0071

CPT1B

carnitine palmitoyltransferase 1B (muscle)

2.80

1.49

0.0074

0.0133

Csf2rb

colony stimulating factor 2 receptor, beta, low-affinity

6.11

2.61

0.0005

0.0044

Ctsd

cathepsin D

3.30

1.72

0.0017

0.0055

Dusp3

Dual specificity protein phosphatase 3

2.03

1.02

0.0107

0.0163

Got2

Glutamic-oxaloacetic transaminase 2

2.27

1.18

0.0077

0.0133

Grik2

Glutamate receptor, ionotropic, kainate 2

2.06

1.04

0.0012

0.0047

Grin3b

Glutamate receptor, ionotropic, N-methyl-D-aspartate 3B protein

4.77

2.25

0.0016

0.0055

Grpel2

GrpE-like 2, mitochondrial (E. coli)

13.4

3.75

0.0009

0.0047

Gucy1a2

Guanylate Cyclase 1, Soluble, Alpha 21

2.05

1.03

0.0023

0.0071

Gucy2f

Guanylate cyclase 2F, retinal

2.34

1.23

0.0075

0.0133

Idh3a

Isocitrate dehydrogenase 3 (NAD+) alpha

2.57

1.36

0.0034

0.0071

Itpk1

Inositol 1,3,4-trisphosphate 5/6 kinase2

5.59

2.48

0.0006

0.0044

Kif5b

Kinesin family member 5B

3.21

1.68

0.0147

0.0199

Lonp1

Lon peptidase 1, mitochondrial

12.0

3.59

0.0016

0.0086

Mrps28

Mitochondrial ribosomal protein S28

2.21

1.14

0.0143

0.0199

mt-Rnr1

Mitochondrially encoded 12S RNA1

4.05

2.02

0.0001

0.0024

mt-Td

Mitochondrially encoded tRNA aspartic acid

14.2

3.82

0.003

0.0086

mt-Tk

Mitochondrially encoded tRNA lysine

3.69

1.88

0.0006

0.0044

mt-Tw

Mitochondrially encoded tRNA tryptophan

3.18

1.67

0.0011

0.0047

mt-Ty

Mitochondrially encoded tRNA tyrosine

3.44

1.78

0.0011

0.0047

Mutyh

Muty homolog (E. coli)

7.92

2.99

0.0141

0.0199

Nrg1

Neuregulin 1

3.34

1.74

0.0006

0.0044

Rap1b

Ras family small GTP binding protein RAP1B2

10.1

3.34

0.0014

0.0053

Rab8a

Member RAS oncogene family

3.54

1.82

0.0000

0.0014

RASA3

Ras GTPase-activating protein 3

2.02

1.01

0.0040

0.0091

Rasgrp4

RAS guanyl releasing protein 4

3.62

1.86

0.0008

0.0047

Timm9

Translocase of inner mitochondrial membrane 9 homolog

3.49

1.80

0.0011

0.0047

Tmlhe

Trimethyllysine hydroxylase, epsilon

6.71

2.75

0.0007

0.0045

  1. Abbreviations: ATP, adenosine triphosphate; FDR, false-discovery rate; tRNA, transfer RNA.36
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