Figure 2 | Translational Psychiatry

Figure 2

From: The positive effect on ketamine as a priming adjuvant in antidepressant treatment

Figure 2

Ketamine effect in the reversion of anhedonic phenotype. Effect of uCMS in sucrose preference (a). Reversion of anhedonic phenotype at the end of first week of treatment in KET, FLX-KET and IMP-KET (P<0.05) (b); rescue of anhedonic behavior by the end of second week of treatment in all animals treated with antidepressant and the addition of KET produces a significantly higher sucrose preference by the end of the second week when comparing the group FLX-KET with FLX (P<0.05) (c). FLX, fluoxetine; IMP, imipramine; KET, ketamine; uCMS, unpredictable chronic mild stress. Mean±s.e.m., n=12, *P<0.05; **P<0.01; ***P<0.001.

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