Figure 2
From: The positive effect on ketamine as a priming adjuvant in antidepressant treatment

Ketamine effect in the reversion of anhedonic phenotype. Effect of uCMS in sucrose preference (a). Reversion of anhedonic phenotype at the end of first week of treatment in KET, FLX-KET and IMP-KET (P<0.05) (b); rescue of anhedonic behavior by the end of second week of treatment in all animals treated with antidepressant and the addition of KET produces a significantly higher sucrose preference by the end of the second week when comparing the group FLX-KET with FLX (P<0.05) (c). FLX, fluoxetine; IMP, imipramine; KET, ketamine; uCMS, unpredictable chronic mild stress. Mean±s.e.m., n=12, *P<0.05; **P<0.01; ***P<0.001.