Figure 3

Females with low NAcc OTR are susceptible to early adversity. After 48 h of cohabitation, the percent of time females spent huddling with their partner over total huddling significantly correlated with NAcc OTR binding in the early-isolated (R=0.779, R²=0.607, P=0.008), but not control (R=0.006, R²<0.0001, P>0.05) females (a). Only females with low OTR binding exposed to early isolation did not form a partner preference (b). Representative autoradiographs of low (c) and high (d) OTR NAcc females. Asterisk indicates paired t-test, P<0.05. Scale bar, 1 mm. NAcc, nucleus accumbens. OTR, oxytocin receptor.