Table 1 Participant ratings in the social cognition task

From: Low-dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized four-way crossover trial with nasal cavity dimension assessment

Outcomes

8IU OPN-OT

24IU OPN-OT

IV OT

Placebo

Linear mixed-model main effect

     

df

F

P

Emotional expression evaluation

       

 Angry ratings of ambiguous faces

2.11 (0.15)

2.46 (0.17)

2.32 (0.18)

2.41 (0.15)

3,14.72

7.62

0.003

 Happy ratings of ambiguous faces

2.61 (0.14)

2.67 (0.12)

2.38 (0.14)

2.51 (0.13)

3,15.17

1.78

0.193

 Angry ratings of angry faces

3.51 (0.2)

3.54 (0.16)

3.68 (0.2)

3.57 (0.16)

3,14.76

0.82

0.505

 Happy ratings of angry faces

4.15 (0.62)

4.26 (0.57)

4.29 (0.54)

4.3 (0.36)

3,15

0.32

0.314

 Angry ratings of happy faces

1.23 (0.02)

1.25 (0.02)

1.24 (0.02)

1.24 (0.02)

3,15

0.97

0.433

 Happy ratings of happy faces

4.11 (0.16)

4.26 (0.14)

4.31 (0.13)

4.3 (0.09)

3,13.84

1.32

0.309

Trustworthiness

3.13 (0.04)

3.15 (0.05)

3.16 (0.05)

3.11 (0.03)

3,14.27

2.57

0.095

  1. Abbreviations: IU, international unit; IV, intravenous; OPN-OT, OT delivered with the Breath Powered OptiNose device; OT, oxytocin.
  2. Unless specified otherwise, values are estimated means based on linear mixed models with standard error in parenthesis.