Table 1 Adversity/Disorder grouping variable descriptives

From: Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disorders

 

No Adversity/No Disorder (n=96)

Adversity/No Disorder (n=60)

No Adversity/Disorder (n=51)

Adversity/Disorder (n=133)

P

Age M (s.d.)

29.60 (10.04)a

31.90 (10.19)a

32.08 (11.29)a

35.95 (12.37)b

0.00

Sex N (%) male

38 (39.6)

22 (36.7)

21 (41.2)

46 (34.6)

0.81

Race N (%) white

74 (77.1)a

37 (61.7)b

46 (90.2)a

108 (81.2)a

0.00

Education N (%), ≥ college degree

54 (56.3)

24 (40.0)

23 (45.1)

44 (33.1)

0.35

Emotional abuse N (%)

—

15 (25.0)a

-—

68 (51.1)b

0.00

Physical abuse N (%)

—

10 (16.7)a

—

48 (36.1)b

0.01

Sexual abuse N (%)

—

13 (21.7)a

—

50 (37.6)b

0.03

Emotional neglect N (%)

—

16 (26.7)a

—

72 (54.1)b

0.00

Physical neglect N (%)

—

10 (16.7)a

—

45 (33.8)b

0.02

Parental death N (%)

—

15 (25.0)

—

23 (17.3)

0.26

Parental desertion N (%)

—

21 (35.0)

—

30 (22.6)

0.13

Number of adversities M (s.d.)

—

1.73 (1.16)a

—

2.62 (1.51)b

0.00

Current MDD N (%)

—

—

9 (17.6)a

44 (33.1)b

0.04

Past MDD N (%)

—

—

18 (35.3)

43 (32.3)

0.70

Current dysthymia/Dep NOS N (%)

—

—

4 (7.8)

16 (12.0)

0.41

Past dysthymia/Dep NOS N (%)

—

—

4 (7.8)

20 (15.0)

0.20

Current PTSD N (%)

—

—

0 (0.0)

4 (3.0)

0.21

Past PTSD N (%)

—

—

2 (3.9)

11 (8.3)

0.30

Current social phobia N (%)

—

—

2 (3.9)

7 (5.3)

0.71

Past social phobia N (%)

—

—

1 (2.0)

5 (3.8)

0.54

Current other anxiety disorder N (%)

—

—

4 (7.8)

4 (3.0)

0.15

Past other anxiety disorder N (%)

—

—

2 (3.9)

11 (8.3)

0.30

Past substance disorder N (%)

—

—

27 (52.9)a

48 (36.1)b

0.04

IDSSR M (s.d.)

6.39 (5.90)a

9.29 (6.69)a

16.43 (12.87)b

21.81 (13.57)c

0.00

STAI—Trait M (s.d.)

27.48 (7.28)a

31.43 (9.79)b

38.14 (12.55)c

39.41 (11.27)c

0.00

STAI—State M (s.d.)

26.56 (6.94)a

27.95 (7.13)a

35.32 (12.98)b

34.43 (10.10)b

0.00

PSS M (s.d.)

16.33 (5.67)a

18.89 (6.81)b

23.88 (9.64)c

23.83 (8.47)c

0.00

  1. Abbreviations: ANOVA, analysis of variance; Dep, depression; IDSSR, Inventory of Depressive Symptomatology, Self-Report; MDD, major depressive disorder; NOS, not otherwise specified; PTSD, post-traumatic stress disorder; STAI, State-Trait Anxiety Inventory.
  2. Note: In four group analyses, P-values indicate ANOVA significance level. In two group analyses, P-values indicate t-test and ?2-significance level. Different superscripts within the same line indicate groups are significantly different from one another at P<0.05. Other anxiety disorders include generalized anxiety disorder, panic disorder, agoraphobia and anxiety disorder NOS.
Back to article page