Table 3 Associations of NR3C1 methylation at individual CpG sites and cortisol concentrations in the Dex/CRH test

From: Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disorders

 

Mean CpG 1 - 13

CpG 1

CpG 2

CpG 3

CpG 4

CpG 5

CpG 6

CpG 7

CpG 8

CpG 9

CpG 10

CpG 11

CpG 12

CpG 13

Post-Dex

0.148*

0.209**

0.136*

0.206**

0.106

0.147*

0.113t

0.162*

0.118t

0.155*

0.098

0.122t

0.143*

0.126t

AUC

0.117t

0.056

0.028

0.083

0.026

0.058

0.122t

0.114t

0.166*

0.098

0.095

0.139*

0.093

0.099

  1. Abbreviations: AUC, area under the curve; Dex/CRH, dexamethasone/corticotropin-releasing hormone.
  2. Note: values indicate Pearson’s Coefficient; tP<0.10, *P<0.05, **P<0.01.
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