Figure 2 | Translational Psychiatry

Figure 2

From: An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

Figure 2

Kynurenine metabolites in the cerebrospinal fluid (CSF) of suicide attempters and healthy controls. (a) CSF picolinic acid (PIC). (b) CSF picolinic acid/quinolinic (PIC/QUIN) acid ratio. (c) CSF kynurenine/tryptophan ratio (KYN/TRP). (d) CSF PIC in suicide attempters over time compared with a single time point measured in control subjects. PIC was lower in suicide attempters than in healthy controls and did not fluctuate over time. (a–d) **P<0.01; ***P<0.001 suicide attempters vs controls. All values represent mean (+s.e.m.).

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