Table 1 Demographic and clinical characteristics of study subjects

From: Insights into psychosis risk from leukocyte microRNA expression

 

Unaffected comparison (UC) n=29

Clinical high risk, not psychotic (CHR-NP) n=37

Clinical high risk, psychotic (CHR- P) n=30

Age, average (s.d.)

19.3 (4.4)

18.1 (3.8)

18.7 (3.7)

Ancestry

 % Caucasian

61%,

65%

52%

 % African

32%

13.5%

19%

 % Asian

7%

13.5%

19%

 % Mixed

0%

8%

10%

Sex, % male

68%

62%

74%

SES, average (s.d.)

7.5 (1.7)

6.5 (1.7)

6.2 (1.6)

Peripheral blood mononuclear cells

 Neutrophils %

56 (11)

55 (13)

55 (10)

 Lymphocytes %

34 (9)

35 (11)

33 (9)

 Monocytes %

8 (2)

7 (3)

8 (3)

 Eosinophils %

2 (3)

2 (2)

2 (2)

 Basophils %

1 (1)

1 (1)

1 (1)

SOPS scores, average (s.d.)

 Totala

4.8 (5.3)

36.8 (12.4)

45.0 (13.0)

 Positivea

1.3 (1.8)

12.6 (4.4)

13.9 (3.7)

 Negativea

1.3 (1.8)

11.5 (5.9)

14.0 (5.9)

 Disorganizeda

.8 (1.1)

4.9 (2.6)

6.2 (3.4)

Generala,b

1.4 (1.7)

7.8 (4.5)

10.9 (4.7)

Prescription medication

 Antipsychoticc

0%

27%

13%

 Antidepressantd

3%

24%

23%

 Stimulant

0%

7%

6%

 Mood stabilizer

0%

0%

3%

 Benzodiazepinee

0%

3%

13%

 NSAID

0%

0%

0%

 Antibiotic

0%

0%

0%

Substance use

 Tobacco usef

7%

30%

39%

 Alcohol use

41%

38%

35%

 Marijuana useg

7%

24%

32%

  1. Abbreviations: NSAID, non-steroidal anti-inflammatory drug; SES, socioeconomic status.
  2. aCHR-P vs UC t-test P-value<0.0001, CHR-NP vs UC t-test P-value<0.0001.
  3. bCHR-P vs CHR-NP t-test P-value=0.02.
  4. CHR-P vs UC FET P-value=0.047, CHR-NP vs UC FET P-value=0.001.
  5. CHR-P vs UC FET P-value=0.011, CHR-NP vs UC FET P-value=0.002.
  6. CHR-P vs UC FET P-value=0.047.
  7. CHR-P vs UC FET P-value=0.001, CHR-NP vs UC FET P-value=0.02.
  8. CHR-P vs UC FET P-value=0.020, CHR-NP vs UC FET P-value=0.056.