Table 2 Genes differentially expressed in the hippocampus in schizophrenia and bipolar disorder

From: Consistently altered expression of gene sets in postmortem brains of individuals with major psychiatric disorders

Gene

All

Schizophrenia vs control

Bipolar disorder vs control

 

Counts

log 2 FC

lfcSE

Wald

P-value

MTC P

log 2 FC

lfcSE

Wald

P-value

MTC P

LOC100131257

219.38

0.41

0.08

5.43

5.52E−08

9.06E−04

0.1

0.07

1.38

1.69E−01

1

LOC100288637

309.86

−0.38

0.08

−4.94

7.80E−07

4.27E−03

−0.31

0.08

−4.06

4.92E−05

0.12

KIF19

1732.95

0.46

0.09

5.01

5.50E−07

4.27E−03

0.18

0.09

1.97

4.88E−02

1

SLC11A1

304.43

0.42

0.09

4.77

1.82E−06

7.48E−03

0

0.09

0.04

9.67E−01

1

FKBP5

2769.46

0.41

0.09

4.34

1.40E−05

3.29E−02

0.29

0.09

3.12

1.78E−03

0.88

GNA14

599.69

0.38

0.09

4.35

1.36E−05

3.29E−02

0.07

0.09

0.78

4.35E−01

1

LOC100188947

150.82

0.35

0.08

4.41

1.01E−05

3.29E−02

0.11

0.08

1.38

1.68E−01

1

HSPA7

867.94

−0.28

0.07

−4.21

2.54E−05

3.94E−02

−0.26

0.06

−4.09

4.38E−05

0.12

SVEP1

715.2

0.38

0.09

4.24

2.27E−05

3.94E−02

0.29

0.09

3.27

1.08E−03

0.71

MT1X

5020.4

0.37

0.09

4.2

2.64E−05

3.94E−02

0.21

0.09

2.36

1.83E−02

1

S100A8

92.33

0.21

0.05

4.23

2.36E−05

3.94E−02

0.03

0.05

0.64

5.22E−01

1

NR4A2

1860.74

−0.37

0.09

−3.97

7.16E−05

9.80E−02

−0.29

0.09

−3.1

1.92E−03

0.89

RPPH1

1246.73

−0.01

0.07

−0.18

8.60E−01

1

0.48

0.06

7.39

1.51E−13

3.29E−09

SCARNA2

192.55

−0.01

0.06

−0.11

9.15E−01

1

0.35

0.06

6.12

9.48E−10

1.04E−05

CDR1

2177.67

0.02

0.08

0.23

8.20E−01

1

0.48

0.08

5.88

4.08E−09

2.97E−05

PAR5

333.34

0.08

0.09

0.89

3.73E−01

1

0.47

0.09

5.42

5.82E−08

3.18E−04

RMRP

604.09

−0.01

0.05

−0.28

7.81E−01

1

0.23

0.05

5.12

2.98E−07

1.30E−03

MTRNR2L6

9.75

0.06

0.07

0.93

3.52E−01

NA

0.3

0.06

4.72

2.37E−06

8.63E−03

MUC16

10.41

0

0.04

−0.1

9.24E−01

NA

0.17

0.04

4.18

2.96E−05

9.24E−02

  1. Abbreviation: NA, not available.
  2. Counts is the average number of normalized read counts per sample; log2FC is log2 transformed fold change; lfcSE is the standard error of the log2 transformed fold change; Wald is the test statistic for differential expression; P-value is the nominal P-value of differential expression; MTC P is the adjusted P-value after multiple testing correction. Bold values are those that are significant after multiple testing correction (MTC P).