Figure 4 | Translational Psychiatry

Figure 4

From: Cerebral [18 F]T807/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy

Figure 4

PET Imaging from a 39-year-old retired NFL player. (a) structural MRI image, (b) [18F]florbetapir PET (c) [18F]T807/AV1451 PET, (d) [18F]T807/AV1451 PET from a healthy age-matched control subject. Note that the [18F]florbetapir image was negative for amyloid accumulation, while the [18F]T807/AV1451 image shows extensive cortical ligand retention, especially at the junction of the gray and white matter, as is characteristic of the distribution of tauopathy in CTE. The PET scales represent ligand uptake in Bq/ml. CTE, chronic traumatic encephalopathy; MRI, magnetic resonance imaging; PET, positron emission tomography.

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