Table 2 Main effect of ATP6V1B2 rs1106634 on the two depression phenotypes in our Level 1 sample (Manchester and Budapest combined sample)

From: Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression

 

Lifetime depression

BSI depression score

Model

N

OR

95% CI

t

P-values

N

β

s.e.

t

P-values

Additive

2226

1.406

1.165–1.696

3.560

<0.001

2222

0.048

0.039

1.214

0.225

Dominant

2226

1.465

1.189–1.804

3.591

<0.001

2222

0.042

0.044

0.965

0.335

Recessive

2226

1.527

0.779–2.993

1.234

0.217

2222

0.179

0.142

1.255

0.210

  1. Abbreviations: 95% CI, 95% confidence interval of OR; BSI, Brief Symptom Inventory; OR, odds ratio; P, nominal P-value; s.e., standard error of β. Population (Budapest or Manchester), gender and age were covariates in all of the six regression equations. The three models correspond to that A is the minor allele in all cases. Significant findings according to the Bonferroni-corrected threshold (P⩽0.0083) are marked with bold.
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