Table 3 Main effect of ATP6V1B2 rs1106634 on lifetime depression in the two Level 1 subsamples in Manchester and Budapest

From: Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression

 

Budapest

Manchester

Model

N

OR

95% CI

t

P-values

N

OR

95% CI

t

P-values

Additive

904

1.541

1.109–2.142

2.574

0.010

1322

1.342

1.070–1.682

2.549

0.011

Dominant

904

1.628

1.129–2.348

2.609

0.009

1322

1.387

1.079–1.784

2.549

0.011

  1. Abbreviations: 95% CI, 95% confidence interval of OR; OR, odds ratio; P, nominal P-value. Gender and age were covariates in all of the four regression equations. The models correspond to that A is the minor allele in both subsamples. All findings are nominally significant (P⩽0.05).