Table 1 Demographic characteristics of suicide attempters and controls

From: Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity

 

Suicide attempters (n=37)

Controls (n=37)

Cohen’s d

P-value

Age (years, mean±s.d.)

39±14

38±17

0.06

0.65a

Female (%)

70

65

N/A

0.62b

BMI (mean±s.d.)

23±5

24±3

0.24

0.80a

MADRS score (mean±s.d.; n=31)

18±10

N/A

N/A

N/A

mtDNA units per μl plasma pre-DST, median, IQR

23 556, 11 152–58 494

503, 303–930

2.64

2.98E−12c

mtDNA units per μl plasma 0800 hours post DST, median, IQR

26 902, 15 371–50 288

683, 356–1111

4.01

1.37E−13c

mtDNA units per μl plasma 1500 hours post DST, median, IQR

34 388, 12 591–64 785 (n=36)

755, 287–948

2.55

4.58E−12c

  1. Abbreviations: BMI, body mass index; DST, dexamethasone suppression test; IQR, interquartile range; MADRS, Montgomery-Åsberg Depression Rating Scale; mtDNA, mitochondrial DNA; N/A, not applicable.
  2. The concentration of mtDNA was skewed and, therefore, log-transformed before calculation of Cohen’s d. Raw data are given in the table as this is more interpretable than transformed values.
  3. aStudent’s t-test.
  4. bPearson’s χ2.
  5. cMann–Whitney U-test.
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