Table 1 Brain volume cohort description
Controls | Schizophrenia | Statistics | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
N | Mean | s.d. | N | Mean | s.d. | X2 | t | df | P | |
Male | 31 | — | — | 31 | — | — | 0.090 | — | 1 | 0.764 |
Female | 14 | — | — | 16 | — | — | ||||
Fixed left hemisphere | 27 | — | — | 24 | — | — | 0.743 | — | 1 | 0.389 |
Fixed right hemisphere | 18 | — | — | 23 | — | — | ||||
Age (years) | — | 52.6 | 13.7 | — | 51.9 | 13.5 | — | −0.242 | 90 | 0.810 |
PMI (h) | — | 28.7 | 12.2 | — | 33.4 | 16.2 | — | 1.569 | 90 | 0.120 |
Brain weight (g) | — | 1431 | 143 | — | 1411 | 152 | — | −0.672 | 90 | 0.503 |
Tissue pH | — | 6.4 | 1.0 | — | 6.5 | 0.2 | — | 0.535 | 89 | 0.594 |
DLPFC: high inflammation | 2 | — | — | 10 | — | — | 5.458 | — | 1 | 0.024 |
DLPFC: low inflammation | 22 | — | — | 18 | — | — | ||||
Inflammation unknowna | 21 | — | — | 19 | — | — | — | — | — | — |
Age of onset | — | — | — | — | 22.8 | 7.0 | — | — | — | — |
Duration of illness (years) | — | — | — | — | 29.1 | 13.7 | — | — | — | — |
Antipsychotics daily mean (mg) | — | — | — | 35 | 744 | 502 | — | — | — | — |
Antipsychotics lifetime (g) | — | — | — | 35 | 8872 | 7903 | — | — | — | — |
Smoking | 19 | — | — | 30 | — | — | 0.089 | — | 1 | 0.105 |
No smoking | 17 | — | — | 12 | — | — | ||||
Smoking unknowna | 9 | — | — | 5 | — | — | — | — | — | — |
Illicit drug | 0 | — | — | 11 | — | — | 0.001 | — | 1 | 0.001 |
No illicit drug | 20 | — | — | 14 | — | — | ||||
Illicit drug unknowna | 25 | — | — | 22 | — | — | — | — | — | — |
