Figure 1
From: Functional evaluation of a PTSD-associated genetic variant: estradiol regulation and ADCYAP1R1
Ovariectomized female mice were given a subcutaneous pellet containing either estradiol or vehicle (sesame oil). The mice where then kept in their home cage in the vivarium (hc) or exposed to fear conditioning (fc) using a tone paired with foot shock. N=7 for each treatment group. Fold change in normalized expression was measured relative to normalized expression in vehicle plus home-caged mice. The data shown are the average fold change ±s.d. in the expression of ADCYAP1R1 in the bed nucleus of the stria terminalis (BNST) per treatment group.
