Table 3 Variables associated with amygdala levels of phospho-GluA1-Ser831

From: A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system

Variables

Amygdala levels of phospho-GluA1-Ser831

P-value

 

Univariate analysis a

 

Gender

Mean (s.e.)

 

 Female

103 (3.6)

 

 Male

117.4 (4.5)

0.02a

AEDs regimen

    

 Monotherapy

114 (5.0)

 

 Two AEDs or more

109 (3.9)

0.51a

Phenobarbital treatment

    

 No

111.7 (3.8)

 

 Yes

105.4 (4.9)

0.32a

 

B

r

r2

P-value

Univariate linear regressions

 Monthly seizure frequency

−0.71

0.21

0.05

0.26b

 Serum glucose

−0.19

0.32

0.10

0.12b

 Storage time of samples (months)

0.36

0.19

0.04

0.30b

 Dexamethasone dose (mg kg−1)

−145.6

0.69

0.48

0.00002b

Multiple linear regression

 Constant

134.8

  

<0.00001

 Female

−0.90

  

0.85

 Serum glucose

−0.10

  

0.33

 Dexamethasone dose (mg kg−1)

−131.1

  

0.0003

  

0.73

0.53

0.001c

  1. Abbreviation: AEDs, antiepileptic drugs.
  2. aUnivariate analysis by Student’s t-test;
  3. bUnivariate analysis by linear regression;
  4. cLevel of significance for the multiple linear regression model.