Table 2 Regression analysis EDT versus ODT task activity and HAMD reduction at 2 weeks

From: Default mode network deactivation during emotion processing predicts early antidepressant response

Regions

MNI coordinates, peak, mm

Cluster statistics

 

x

y

z

Cluster size

T

HAMD baseline, age, and sex as covariates

 Gyrus rectus, R

8

28

−18

109

7.48*

 Middle temporal cortex, L

−66

−18

−18

421##

6.83

 Precuneus, L

−4

−46

14

1431###

6.67

 Hippocampus, L

−18

−24

−6

308#

5.58

 Middle temporal cortex, R

68

−34

−6

233#

5.18

  1. Abbreviations: AAL, Automated Anatomical Labeling Atlas; EDT, emotion discrimination task; FWE, family-wise error; HAMD, Hamilton Depression Rating Scale; ODT, object discrimination task; L, left; R, right.
  2. Regions according to AAL.
  3. FWE-corrected, voxel-level:
  4. *P<0.05.
  5. FWE-corrected, cluster-level (voxel size 2 × 2 × 2 mm):
  6. ###P<0.001; ##P<0.01; #P<0.05.
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