Figure 6 | Translational Psychiatry

Figure 6

From: The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder

Figure 6

Distribution of plasma levels of TARC over a circadian interval for patients with PTSD and healthy controls. (a) Differences between average log plasma TARC levels in female PTSD patients vs female healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. Differences between PTSD Females and healthy control females at every hour are not significant (P0.05). (b) Differences between average log plasma TARC levels in male PTSD patients are lower than male healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. PTSD males are differ significantly at each hour across circadian time from healthy controls only at ca. Z−12 and Z, (P0.05). (c) Differences between average log plasma TARC levels in all PTSD patients vs all healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. There are no significant differences at each hour across circadian time, (P0.05). (d) Significance of log plasma concentration differences for TARC lover circadian time. Vertical axis is log P-value. Red horizontal line is the same as P=0.05 on a arithmetic scale. Male PTSD (dotted black line); female PTSD (dashed black line); all PTSD (solid black line). Male PTSD patients differ significantly from male healthy controls at every hour across circadian time only at ca. Z -12 and Z, (P0.05). HC, healthy controls; PTSD, post-traumatic stress disorder.

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