Figure 6

Distribution of plasma levels of TARC over a circadian interval for patients with PTSD and healthy controls. (a) Differences between average log plasma TARC levels in female PTSD patients vs female healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. Differences between PTSD Females and healthy control females at every hour are not significant (P⩽0.05). (b) Differences between average log plasma TARC levels in male PTSD patients are lower than male healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. PTSD males are differ significantly at each hour across circadian time from healthy controls only at ca. Z−12 and Z, (P⩽0.05). (c) Differences between average log plasma TARC levels in all PTSD patients vs all healthy controls. Error bars are ±s.e.m. P-values for the difference at each hour are shown in d. There are no significant differences at each hour across circadian time, (P⩽0.05). (d) Significance of log plasma concentration differences for TARC lover circadian time. Vertical axis is log P-value. Red horizontal line is the same as P=0.05 on a arithmetic scale. Male PTSD (dotted black line); female PTSD (dashed black line); all PTSD (solid black line). Male PTSD patients differ significantly from male healthy controls at every hour across circadian time only at ca. Z -12 and Z, (P⩽0.05). HC, healthy controls; PTSD, post-traumatic stress disorder.