Figure 3

Results of the polygenic risk score analysis using the PGC-SCZ2 data as the discovery sample and OCD data as target sample. The x axis represents the different Pthreshold. Significance of the score is shown above each column. The y axis represents the percentage of variance explained on the observed scale (Nagelkerke's pseudo-R2). (a) Values including the extended MHC region. (b) Values after removing the extended MHC region. MHC, major histocompatibility complex; OCD, obsessive-compulsive disorder; PGC-SCZ2, Psychiatric Genetics Consortium schizophrenia data set.