Figure 1 | Translational Psychiatry

Figure 1

From: Advanced brain aging: relationship with epidemiologic and genetic risk factors, and overlap with Alzheimer disease atrophy patterns

Figure 1

SPARE-BA values for all SHIP participants (n=2705) plotted against age. Red line represents local polynomial fitted curve. Higher/lower values indicate less/more aging-specific brain atrophy patterns, captured by the SPARE-BA index. Brain rendering shows the gray matter RAVENS (regional volumetric) maps for age groups 20–80. The color map represents lower RAVENS values (that is, less gray matter) in blue and higher RAVENS values (that is, more gray matter) in red. We observe a consistent decrease in gray matter volume in the cortex with age, which are particularly prominent in certain frontal, parietal and temporal brain regions. SPARE-BA, Spatial Pattern of Atrophy for Recognition of BA.

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