Figure 3
From: Regulation of prefrontal cortex myelination by the microbiota
Increased myelin sheath thickness in the prefrontal cortex (PFC) of male germ-free (GF) mice. (a) Electron micrographs of axons in the PFC of conventionally raised (CON) and GF mice. Scale bars=200 and 1000 nm. (b) Average g-ratio per animal in the PFC. (c) Scatter plot of g-ratio values in the PFC in CON (n=187 axons) and GF (n=390 axons) against axon diameter. (d) Average axonal diameter per animal. (e) Scatter plot of axon diameter against the number of lamina counted for that individual axon. (f) g-ratio for individual axonal population based on diameter range. Bar graphs shown as mean±s.e.m. NS (not significant) P>0.05; *P<0.05; **P<0.01.
