Figure 1
From: Multiple markers of cortical morphology reveal evidence of supragranular thinning in schizophrenia
Morphological effect of disproportionate supragranular thinning (I–III, green/blue; infragranular, V and VI, light gray). Decreased dendrites and synapses in schizophrenia can result in thinner supragranular layers, which may in turn be reflected in changes to large-scale cortical morphology. In particular, supragranular layers are thicker in sulci than in gyri, thus pruning will lead to disproportionately reduced cortical thickness in sulci compared with gyri. Similarly, pruning of the supragranular layers will affect the curvature of the pial surface more than the curvature of the boundary between gray and white matters, again disproportionately more in sulci than gyri.
