Figure 1
From: Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders

Schematic representation of the interactions among mast cells–microglia–neurons and the blood–brain barrier. Curved arrows, along with mediators associated with them, indicate action from one type of cell to another. The inhibitory action of luteolin (in box) is indicated by the inhibitory symbols (T). CRH, corticotropin-releasing hormone; IL, interleukin; NT, neurotensin; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor.