Table 1 Statistical significance for the linear associations between striatal D₂/D₃R measures and brain activation responses (BOLD) during the VA task under SD and RW conditions

Region		MNI coordinates (mm)			Brain activation			Session	D ₂ /D ₃ R-BOLD SLR
									Cluster level		Voxel level
Name	BA/nucleus	x	y	z	VA, T	VA load, T	SD>RW, T		P_FWE-corr.	k	P_FWE-corr.	T
Caudate (CD)
Thalamus	Anterior	0	−6	6	5.7	NS	NS	RW	0.001	220	<0.0005	4.5
Middle Occipital	19	−27	−84	24	−4.1	−1.7	NS	SD	0.023	109	0.006	−4.5
Ventral striatum (VS)
Precuneus	7	3	−63	39	−7.0	NS	NS	RW	0.001	222	<0.0005	5.3
Thalamus	Anterior	0	−3	6	4.0	NS	NS	RW	0.003	179	0.001	4.2
Cuneus	18	6	−81	27	−12.0	−1.7	2.0	RW	0.03	101	0.008	−6.4
Precuneus	7	6	−54	45	NS	NS	2.2	SD	0.001	217	<0.0005	5.8
Globus pallidus (GP)
Thalamus	Ventral posterior	24	−15	0	NS	NS	NS	RW	0	389	<0.0005	4.7
Precuneus	7	0	−63	36	−12.3	NS	NS	RW	0.004	170	0.001	4.7
Cuneus	18	6	−81	27	−12.0	−1.7	2.0	RW	0.031	101	0.008	−5.6
Middle Occipital	19	−27	−78	33	−9.0	−2.4	NS	RW	0.015	125	0.004	−5.6
Middle Occipital	39	42	−78	18	3.0	NS	NS	RW	0	283	<0.0005	−4.9
Putamen (PU)
Thalamus	Ventral posterior	24	−12	0	NS	NS	1.7	RW	0	355	<0.0005	4.5
Middle Occipital	19	−27	−78	33	−9.0	−2.4	NS	RW	0.002	194	0.001	−6.7
Middle Occipital	39	42	−78	18	3.0	NS	NS	RW	0	340	<0.0005	−5.3
Lingual	37	24	−51	−9	−3.9	NS	NS	RW	0.005	164	0.001	−4.6
CD
Thalamus	Pulvinar	18	−24	15	8.3	NS	2.8	RW>SD	0.02	430	0.001	5.0
VS
Thalamus	Pulvinar	18	−24	18	7.1	NS	2.5	RW>SD	0.002	665	<0.0005	5.5

Abbreviations: BOLD, blood-oxygen-level dependent; FWE-corr., family-wise error corrected; NS, not significant; RW, rested wakefulness; SD, sleep deprivation; SLR, simple linear regression; VA, visual attention.
Sample size: 14 healthy non-smoking men.

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