Table 1 Results of the gene-based analysis using MAGMA
GENE | CHR | START | STOP | NSNPS | NPARAM | ZSTAT | P |
---|---|---|---|---|---|---|---|
PKP4 | 2 | 159303476 | 159547941 | 21 | 13 | 4.7924 | 8.24 × 10−7 |
DPYD | 1 | 97533299 | 98396615 | 105 | 68 | 4.7162 | 1.20 × 10−6 |
GRAMD1B | 11 | 123315191 | 123508478 | 34 | 28 | 3.8856 | 5.10 × 10−5 |
STX8 | 17 | 9143788 | 9489275 | 38 | 33 | 3.7984 | 7.28 × 10−5 |
BMP2 | 20 | 6738745 | 6770910 | 7 | 6 | 3.588 | 1.67 × 10−4 |
TRAF3IP1 | 2 | 239219185 | 239319541 | 11 | 8 | 3.5389 | 2.01 × 10−4 |
ZP3 | 7 | 76016841 | 76081388 | 9 | 7 | 3.5037 | 2.29 × 10−4 |
PINX1 | 8 | 10612473 | 10707394 | 19 | 11 | 3.5034 | 2.30 × 10−4 |
GTF3C4 | 9 | 135535728 | 135575471 | 4 | 4 | 3.4851 | 2.46 × 10−4 |
DNAH1 | 3 | 52340335 | 52444513 | 11 | 8 | 3.4543 | 2.76 × 10−4 |
YKT6 | 7 | 44230577 | 44263893 | 6 | 3 | 3.3841 | 3.57 × 10−4 |
CCSER1 | 4 | 91038684 | 92533370 | 111 | 78 | 3.3804 | 3.62 × 10−4 |
LRRC59 | 17 | 48448594 | 48484914 | 8 | 6 | 3.3716 | 3.74 × 10−4 |
TMEM71 | 8 | 133712191 | 133782914 | 9 | 8 | 3.3668 | 3.80 × 10−4 |
BAP1 | 3 | 52425020 | 52454121 | 3 | 3 | 3.345 | 4.11 × 10−4 |
AQR | 15 | 35138552 | 35271995 | 8 | 6 | 3.3299 | 4.34 × 10−4 |
FGFR1 | 8 | 38258656 | 38336352 | 12 | 10 | 3.3162 | 4.56 × 10−4 |