Figure 1 | Translational Psychiatry

Figure 1

From: Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression

Figure 1

Odds ratio for lifetime depression per ATXN7 category. The odds ratio for lifetime depression increases significantly when both the relatively long ATXN7 allele and the relatively short ATXN7 allele exceed the median CAG repeat number of 10. The odds of having lifetime depression almost doubles. The group having both alleles with a CAG repeat number 10 was the largest and, therefore, was set as the reference category. I, both alleles of ATXN7 contain a CAG repeat number 10; II, the relatively longer ATXN7 allele contains a CAG repeat number >10 and the relatively shorter allele contains a CAG repeat number 10; III, both alleles of ATXN7 contain a CAG repeat number >10. Error bars indicate±s.e. **P<0.01 by the Fisher’s exact test in comparison with the reference category; CAG, cytosine–adenine–guanine.

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