Table 2 Clinical and demographic characteristics—baseline cognitive function and 6-year cognitive change
Characteristic | Na | Baseline;N=1577;N (%) | Na | Cognitive change;N=1035;N (%) |
|---|---|---|---|---|
Male | 1577 | 538 (34.1) | 1035 | 341 (33.0) |
Female | 1039 (65.9) | 694 (67.0) | ||
Education | 1577 | 1035 | ||
⩽11 Years | 615 (39.0) | 364 (35.2) | ||
>11 Years and ⩽16 years | 432 (27.4) | 283 (27.3) | ||
>16 Years | 530 (33.6) | 388 (37.5) | ||
Current smokers | 1575 | 385 (24.4) | 1033 | 214 (20.7) |
Hypertension | 1570 | 810 (51.6) | 1028 | 502 (48.8) |
Diabetes | 1561 | 344 (22.0) | 1023 | 209 (20.4) |
APOE (at least 1 ɛ4 allele) | 1404 | 592 (42.2) | 912 | 392 (43.0) |
APOE (ɛ4/ɛ4) | 1404 | 63 (4.5) | 912 | 47 (5.2) |
Mean (s.d.) | Mean (s.d.) | |||
Age (years) | 1577 | 55.4 (5.6) | 1035 | 55.0 (5.4) |
BMI (kg/m2) | 1577 | 30.1 (6.1) | 1035 | 30.2 (6.1) |
LDL cholesterol (mmol l−1) | 1550 | 3.5 (1.0) | 1021 | 3.5 (1.0) |
Ethanol (g per week) | 1573 | 23.5 (84.6) | 1031 | 21.6 (76.2) |
eGFRCKD-EPI (ml min−1 per 1.73m2) | 1577 | 105.1 (17.3) | 1035 | 105.0 (16.7) |
Cognitive tests | ||||
Baseline (visit 2) | ||||
DWRT (words) | 1575 | 6.2 (1.6) | 1034 | 6.3 (1.6) |
DSST (digit-symbol pairs) | 1565 | 31.4 (13.6) | 1030 | 32.9 (13.3) |
WFT (words) | 1570 | 27.9 (13.3) | 1031 | 29.3 (13.2) |
6-Year change (visit 2–visit 4) | ||||
DWRT (words) | --- | --- | 1034 | −0.25 (1.72) |
DSST (digit-symbol pairs) | --- | --- | 1018 | −2.06 (8.82) |
WFT (words) | --- | --- | 1026 | −0.89 (8.41) |
