Figure 2
From: Neuroimaging studies of GABA in schizophrenia: a systematic review with meta-analysis
(a–d) Forest plots showing effect sizes (Hedge’s g) for 1H-MRS GABA studies in schizophrenia versus control. Error bars represent 95% confidence intervals. Black squares indicate data from clinical patient samples (FEP or SCZ) while white squares indicate data from CHR or sibling samples. CHR, clinical high risk; FEP, first episode psychosis; 1H-MRS, proton magnetic resonance spectroscopy; SCZ, schizophrenia or schizoaffective disorder; sibling, unaffected siblings of patients with schizophrenia; med, currently receiving antipsychotic medication; unmed, currently unmedicated with antipsychotics.
