Table 2 Clinical characteristics of PTSD and MDD samples. Mean (s.d.) were reported for Age

From: An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders

PTSD

Current (Case) n=171

Past n=100

Never (Control) n=202

P-value

Age

49.5 (7.6)

48.3 (7.8)

50.0 (8.4)

0.504

Race

 Caucasian

139 (81.3)

78 (78.0)

165 (81.7)

1

 Other

32 (18.7)

22 (22.0)

37 (18.2)

 

Smoker

 Yes

28 (16.4)

10 (10.0)

9 (4.5)

<0.01

 No

143 (83.6)

90 (90.0)

193 (95.5)

 

MDD a

Current (Case) n=116

Past n=60

Never (Control) n=282

P-value

Age

50.0 (8.0)

49.2 (8.2)

49.2 (8.0)

0.433

Race

 Caucasian

94 (81.0)

46 (76.7)

230 (81.6)

1

 Other

22 (19.0)

14 (23.3)

52 (18.4)

 

Smoker

 Yes

18 (15.5)

11 (18.3)

18 (6.4)

<0.01

 No

98 (84.5)

49 (81.7)

264 (93.6)

 
  1. Abbreviations: MDD, major depressive disorder; PTSD, posttraumatic stress disorder.
  2. Number (%) were reported for Race and Smoker within each group. The P-values were computed from t-test (for Age) and χ2-test (for Race, Smoker and PTSD and MDD comorbidity) comparing current to control. PTSD and MDD cases correspond to current PTSD and current MDD, respectively.
  3. aMDD for 15 patients were not recorded.
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