Table 2 Frequency of the DCDC2 deletion reported in this study

From: The DCDC2 deletion is not a risk factor for dyslexia

Cohort

Structure

Recruitment

DCDC2 deletion frequency

Oxford Family Dyslexia

219 families

Clinical—children with reading difficulties

8.9% parents (N=414)

9.8% probands (N=153)a

Oxford Cases Dyslexia

272 singletons

Clinical—children with reading difficulties

6.1%

Aston Dyslexia

105 singletons

Clinical—children with reading difficulties

7.6%

York

103 families

Longitudinal—children with language difficulties, family history of dyslexia and typically developing

7.4% parents (N=174)

7.7% all probands (N=103)

5.5% RD group (N=18)

10.7% TD group (N=72)

Combined

203 singletons

Individuals scoring READ<-1.5s.d. in the above cohorts

9.6%

Hong Kong

220 singletons/twins

Typically developing

37.6%

1000 Genomes

503 singletons

504 singletons

General population

8.05% Europe

33.5% East Asia

  1. Abbreviations: RD, reading difficulties; TD, typically developing.
  2. aThe number of probands is lower than the number of families because of missing data.
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