Table 2 Functional enrichment of genes in co-expression modules.
From: RNA-seq analysis of amygdala tissue reveals characteristic expression profiles in schizophrenia
Module | Term | Fold enrichment | P-value | BenjaminiQ-value |
|---|---|---|---|---|
Yellow | GO:0005576~extracellular region | 2.56 | 3.59E−11 | 6.79E−09 |
GO:0044421~extracellular region part | 2.99 | 2.08E−07 | 1.97E−05 | |
GO:0007268~synaptic transmission | 5.01 | 1.63E−06 | 2.21E−03 | |
GO:0010033~response to organic substance | 3.17 | 2.51E−06 | 1.70E−03 | |
GO:0005509~calcium ion binding | 2.85 | 7.29E−06 | 2.29E−03 | |
GO:0019226~transmission of nerve impulse | 4.26 | 1.05E−05 | 4.72E−03 | |
GO:0005615~extracellular space | 2.89 | 4.95E−05 | 3.12E−03 | |
GO:0007155~cell adhesion | 2.84 | 6.54E−05 | 2.19E−02 | |
GO:0022610~biological adhesion | 2.84 | 6.67E−05 | 1.79E−02 | |
GO:0016477~cell migration | 4.32 | 9.98E−05 | 2.23E−02 | |
Green | GO:0001568~blood vessel development | 15.78 | 6.40E−09 | 3.65E−06 |
GO:0001944~vasculature development | 15.40 | 7.90E−09 | 2.25E−06 | |
GO:0048514~blood vessel morphogenesis | 14.65 | 7.65E−07 | 1.45E−04 | |
GO:0001525~angiogenesis | 15.67 | 3.16E−05 | 4.49E−03 | |
GO:0005886~plasma membrane | 2.01 | 3.00E−04 | 3.13E−02 | |
Pink | GO:0006955~immune response | 6.76 | 6.38E−06 | 1.87E−03 |
Red | GO:0006955~immune response | 3.84 | 2.92E−06 | 4.13E−03 |
GO:0032403~protein complex binding | 8.08 | 3.46E−06 | 8.55E−04 | |
GO:0002684~positive regulation of immune system process | 6.80 | 4.34E−06 | 3.07E−03 | |
GO:0031349~positive regulation of defense response | 14.10 | 9.30E−06 | 4.38E−03 | |
GO:0001775~cell activation | 5.64 | 2.23E−05 | 7.88E−03 | |
GO:0006952~defense response | 3.59 | 5.81E−05 | 1.64E−02 | |
GO:0030198~extracellular matrix organization | 9.90 | 7.01E−05 | 1.64E−02 | |
GO:0005886~plasma membrane | 1.67 | 1.51E−04 | 2.96E−02 | |
GO:0048584~positive regulation of response to stimulus | 5.61 | 1.86E−04 | 3.70E−02 | |
GO:0045321~leukocyte activation | 5.47 | 2.21E−04 | 3.84E−02 | |
GO:0007155~cell adhesion | 3.15 | 2.28E−04 | 3.53E−02 | |
GO:0022610~biological adhesion | 3.15 | 2.31E−04 | 3.23E−02 | |
GO:0001568~blood vessel development | 5.40 | 2.40E−04 | 3.05E−02 | |
GO:0005911~cell−cell junction | 6.33 | 2.48E−04 | 2.43E−02 | |
GO:0045089~positive regulation of innate immune response | 15.98 | 2.52E−04 | 2.93E−02 | |
GO:0033256~I-kappaB/NF-kappaB complex | 112.78 | 2.54E−04 | 1.67E−02 | |
GO:0001944~vasculature development | 5.27 | 2.83E−04 | 3.04E−02 | |
GO:0046649~lymphocyte activation | 5.91 | 3.82E−04 | 3.80E−02 | |
GO:0045088~regulation of innate immune response | 13.62 | 4.69E−04 | 4.33E−02 | |
GO:0001525~angiogenesis | 6.95 | 4.81E−04 | 4.17E−02 | |
GO:0046637~regulation of alpha−beta T-cell differentiation | 23.53 | 6.08E−04 | 4.95E−02 | |
GO:0030098~lymphocyte differentiation | 8.57 | 6.43E−04 | 4.94E−02 |
