Table 3 Predicting the psychosis-spectrum

From: Emergent, remitted and persistent psychosis-spectrum symptoms in 22q11.2 deletion syndrome

 

Outcomes

Predictors

Emergence or persistence of psychosis

Change in total SOPS score

Change in factor 1: Unusual thoughts and experiences

Change in factor 2: Impairment in social, occupational and daily functioning

 

Coeff.

z

P

Coeff.

t

P

Coeff.

t

P

Coeff.

t

P

T1 age

0.15

1.76

0.08

0.02

1.25

0.22

0.01

0.31

0.76

0.03

1.53

0.13

Sex

2.12

1.99

0.05

0.25

1.35

0.18

0.59

2.92

0.01

0.01

0.04

0.97

T1 factor 1

1.55

2.38

0.02

−0.18

−1.54

0.13

0.78

6.18

0.00

0.00

0.03

0.98

T1 factor 2

−0.17

−0.23

0.82

0.42

2.65

0.01

−0.23

−1.38

0.18

0.50

2.75

0.01

T1 GAF

−0.04

−1.00

0.32

0.01

1.25

0.22

0.00

−0.34

0.73

0.01

1.19

0.24

T1 mood disorder

1.31

1.06

0.29

0.70

2.55

0.01

1.12

3.79

0.00

0.50

1.61

0.11

T1 anxiety disorder

1.82

1.96

0.05

0.21

0.99

0.33

0.22

0.98

0.33

0.20

0.83

0.41

T1 ADHD

−0.81

−0.90

0.37

0.18

0.85

0.40

−0.02

−0.08

0.93

0.31

1.33

0.19

Lifetime psychotropic use

0.94

1.03

0.30

−0.03

−0.14

0.89

−0.03

−0.14

0.89

0.07

0.29

0.77

T1 global cognition

2.50

2.34

0.02

0.59

3.37

0.00

0.39

2.18

0.03

0.57

2.98

0.00

Change in global cognition

−1.21

−1.12

0.26

0.81

3.79

0.00

0.52

2.37

0.02

0.83

3.56

0.00

CNB trials

−1.74

−1.93

0.05

0.02

0.12

0.91

0.07

0.39

0.70

0.16

0.91

0.37

  1. Abbreviations: ADHD, attention-deficit hyperactivity disorder; CNB, Computerized Neurocognitive Battery; Coeff, coefficient; GAF, global assessment of function; SOPS, Scale of Prodromal Symptoms; T1, time 1/initial evaluation.
  2. CNB trials was added as covariate because of possible practice effects and non-uniform total number of trials administered to participants who are evaluated at 2–4 time points. Bolded entries highlight statistical significance.