Table 1 Mean (standard deviation) change in binding potential from baseline in MP+LPS, MP+PBO, LPS pre-treatment conditions
From: Systemic inflammation enhances stimulant-induced striatal dopamine elevation
ROI | Volume (mL) | Mean ΔBP (n=8) | P-value | Mean ΔBP (n=2) | |
|---|---|---|---|---|---|
MP+LPS | MP+PBO | LPS | |||
Striatum | 42.6 | 17.1 (3.6) | 8.8 (3.6) | 0.007 | 6.1 (1.8) |
Putamen | 21.9 | 17.9 (5.0) | 9.5 (4.5) | 0.013 | 4.5 (3.2) |
Left | 10.7 | 18.0 (5.4) | 9.7 (7.5) | 0.071 | 4.7 (0.1) |
Right | 11.3 | 17.7 (5.6) | 9.1 (4.9) | 0.001 | 4.6 (5.6) |
Caudate | 20.7 | 16.1 (5.4) | 7.7 (3.7) | 0.020 | 8.6 (0.2) |
Left | 10.2 | 13.9 (7.8) | 4.8 (9.2) | 0.099 | 9.6 (3.3) |
Right | 10.5 | 18.5 (5.3) | 11.0 (11.6) | 0.058 | 7.3 (3.7) |
Ventral striatum | 2.9 | 12.7 (8.1) | 11.4 (9.3) | 0.809 | 1.7 (5.4) |
Left | 1.4 | 16.6 (7.1) | 11.5 (11.4) | 0.409 | 3.9 (7.5) |
Right | 1.5 | 7.3 (13.8) | 10.8 (13.5) | 0.574 | −1.3 (2.9) |
