Figure 2 | Translational Psychiatry

Figure 2

From: Ablation of neuropsin–neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation

Figure 2

Time course for the seizure score in neuropsin-knockout (KO) mice administered kainate (KA). Mice received repeated injections of KA. KA-treated neuropsin-KO mice (black circles; n=11 mice) showed progression of seizures compared with KA-treated wild-type mice (white circles; n=11 mice, two-way ANOVA, F(1,20)=5.744; *P=0.0264). Seizure score of neuropsin-KO mice was significantly higher than that of wild-type mice only at the 4 h after KA administration (*P=0.046; two-way ANOVA with the Sidak post-hoc test). Error bars indicate standard error of the mean.

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