Figure 2 | Translational Psychiatry

Figure 2

From: Outcome reporting bias in randomized-controlled trials investigating antipsychotic drugs

Figure 2

Consistencies between primary and secondary outcomes in records and publications. (a) Converted or non-reported outcomes in publications relative to records. (b) Reported outcomes not prespecified in records relative to publications. Data are presented as 100% stacked columns. The left bar in (a) denotes that of 63 primary outcomes, three (4.7%) were converted to secondary outcomes in the publications relative to the ClinicalTrials.gov records; eight (13%) were found in ClinicalTrials.gov records but not in the respective publications; and 52 (83%) were both prespecified in records and reported in publications. The right bar denotes that out of 197 secondary outcomes, nine (4.6%) were converted to primary outcomes; 58 (29%) were prespecified on ClinicalTrials.gov but not reported in the respective publications; and 130 (66%) were both prespecified in the ClinicalTrials.gov records and reported in the publications. The left bar in (b) denotes that out of 66 primary outcomes, 14 (21%) were reported in the publications but had not been prespecified in their ClinicalTrials.gov records; and 52 (79%) were both prespecified in records and reported in publications. The right bar denotes that of 284 published secondary outcomes 154 (54%) had not been prespecified in the ClinicalTrials.gov records and 130 (46%) were both prespecified in records and published in publications.

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