Figure 4
From: Outcome reporting bias in randomized-controlled trials investigating antipsychotic drugs
Registration of RCTs relative to trial initiation and updating of outcomes after trial initiation. Figure depicting the extent to which outcome sections on ClinicalTrials.gov are altered after trial initiation. The x-axis denotes the trial period during which either a proportion of outcomes are updated or all outcome measures are newly uploaded to the ClinicalTrials.gov records. The y-axis denotes percentages relative to all outcomes. Data are presented as stacked columns. Figures in the stacks represent percentages of RCTs. The first bar on the left denotes that of 48 studies 17 (35%) had all outcome measures registered before the trial start date. The second bar denotes that two studies (4.2%) updated all of their outcome measures in the first half of the trial and four studies (8.3%) did this for a proportion of their outcomes. The third bar denotes that five studies (10%) updated all of their outcome measures in the second half of the trial and three studies (6.3%) updated a proportion of their outcomes in the second half of their trial. The fourth bar denotes that eight studies (17%) updated all of their outcomes and nine studies (19%) a proportion of their outcomes after the trial stop date.
