Table 2 Discrepancies between prespecified and published primary/secondary outcomes

From: Outcome reporting bias in randomized-controlled trials investigating antipsychotic drugs

 

No. of trials with discrepancies (%)

Total no. of discrepancies (% of prespecified/published outcomes)

Mean no. of discrepancies per included trial (N=48)

Primary outcomes

 Prespecified outcome not published

4 (8%)

8/63 (13%)

0.2

 Prespecified outcome converted to secondary outcome in publication

3 (6%)

3/63 (5%)

0.1

 Published outcomes not prespecified

10 (21%)

14/66 (21%)

0.3

Secondary outcomes

 Prespecified outcome not published

18 (38%)

58/197 (29%)

1.2

 Prespecified outcome converted to primary outcome in publication

4 (8.3%)

9/197 (5%)

0.2

 Published outcomes not prespecified

37 (77%)

154/284 (54%)

3.2