Figure 2
hBDNFVal66Met genotype and chronic CORT exposure interact to selectively reduce the expression of Tyrosine Hydroxylase (TH) and calretinin in the mPFC but not hippocampus. While there was no effect of genotype or chronic CORT treatment on TH (a, b) or calretinin (d, e) expression in the DHP or VHP, the expression of both TH (c) and calretinin (f) was found to be reduced in hBDNFVal/Val mice following CORT in the mPFC. All data are presented as mean±s.e.m.; *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. Per group, n=13–14.
