Figure 4
From: Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice
Expression of Slc6a4 mRNA across the rostrocaudal extent of the dorsal raphe nucleus. (a) Photomicrographs illustrating Slc6a4 (solute carrier family 6, member 4; 5-Htt) mRNA expression in Tph2+/+ mice (left), Tph2+/− mice (middle) and Tph2−/− mice (right) at −4.364 mm bregma. (b–e) Mean expression of Slc6a4 mRNA across the rostrocaudal extent of (b) the entire dorsal raphe nucleus (DR) and (c) MnR, (d) rDRD and (e) cDRD as well as (f) rDRV and (g) cDRV of Tph2+/+, Tph2+/− and Tph2−/− mice (n=6–8 per genotype). DR, dorsal raphe nucleus; DRD, dorsal raphe nucleus, dorsal part; DRV, dorsal raphe nucleus, ventral part; MnR, median raphe nucleus. n=6–8/genotype; *P<0.01. Scale bar, 200 μm (a).
