Figure 3 | Translational Psychiatry

Figure 3

From: Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis

Figure 3

Effects of 5-aza-2’-deoxycytidine treatment in lymphoblastoid cells from adult patients with bipolar disorder and controls. Cells were treated for 96 h (1 or 5 μM). (a) Cell viability assessed by MTT assay; (b) 5-methylcytosine (%) level; (c–f) mRNA levels for MED1, TAF15, HSPA1L and GTF2A1. *P<0.05, **P<0.01, and ***P<0.001 when compared to vehicle treatment in the same group. #P<0.05 when compared to the same treatment in the control group. MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium.

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