Figure 2

Cellular parameters in postmortem brains of schizophrenia patients. Forest plot showing cellular parameters measured in the brains of schizophrenic patients compared to controls. Values are expressed as standardized mean differences (SMDs) with 95% confidence intervals (CI). The column ‘No. HC/SZ’ denotes the number of patients in the healthy control and schizophrenic groups. The column ‘Immune Parameter’ denotes the staining or scoring method used to quantify immune involvement. The plot is divided in subsections showing study cohorts in which microglia, macroglia and lymphocytes are measured. The column ‘Location’ indicates the brain area under investigation as reported by the authors of the individual study, ‘Location Group’ indicates the re-classification assigned by us for meta-regression. The diamonds at the bottom indicate the pooled estimate obtained by multilevel random effects meta-analysis.