Figure 1 | Translational Psychiatry

Figure 1

From: Deep brain stimulation for treatment-resistant major depressive disorder: a comparison of two targets and long-term follow-up

Figure 1

Study design. IC/BST stimulation is indicated in blue, ITP stimulation in green and stimulation OFF in red. Duration of different phases is indicated above the study design. Time points when psychiatric measures were collected, are indicated by arrows. Blinding modalities are indicated below. Evaluators (neuropsychologist and psychiatrist) and patients were blinded during the crossover phases of the study. The neurosurgeon (BN) generated the stimulation condition sequence for each patient separately (using www.random.org services) and allocated interventions accordingly. IC/BST, internal capsule/bed nucleus of stria terminalis stimulation; ITP, inferior thalamic peduncle stimulation; OFF, no stimulation; w, weeks; m, months.

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