Table 3 Sex-specific differences between fractional anisotropy values in adults with an ASC diagnosis with and without severe current symptoms as measured using the ADOS total score

From: Sex differences in frontal lobe connectivity in adults with autism spectrum conditions

Frontal tracts

Males (N=59) 16 ADOS− and 43 ADOS+

Females (N=36) 22 ADOS− and 14 ADOS+

 

F

P-value

Bayes factor

F

P-value

Bayes factor

Anterior segment AF left

0.37

0.546

0.23

1.90

0.178

0.02

Anterior segment AF right

1.13

0.293

0.19

0.92

0.346

0.05

Long segment AF left

0.59

0.444

0.25

0.71

0.407

0.15

Long segment AF right

0.11

0.742

0.08

0.21

0.648

<0.01

Cingulum left

0.27

0.607

0.13

0.48

0.492

0.04

Cingulum right

0.03

0.870

0.01

0.12

0.734

0.02

Uncinate left

0.01

0.939

0.41a

3.48

0.072

0.01

Uncinate right

0.29

0.593

0.09

0.80

0.377

0.02

IFOF left

0.36

0.550

0.12

0.02

0.899

0.15

IFOF right

0.32

0.577

0.45a

0.09

0.761

0.09

Non-frontal tracts

 Posterior segment AF left

0.35

0.557

0.13

0.05

0.826

0.54a

 Posterior segment AF right

0.06

0.802

0.19

0.43

0.515

0.03

 ILF left

0.13

0.718

0.05

0.23

0.634

0.32

 ILF right

0.18

0.671

0.21

0.93

0.342

0.05

  1. Abbreviations: ADOS, Autism Diagnostic Observation Schedule; ADOS−, ASC participants not reaching ADOS cutoff score of 7; ADOS+, ASC participants reaching ADOS Total cutoff score of 7; AF, arcuate fasciculus; ASC, autism spectrum conditions; IFOF, inferior frontal occipital fasciculus; ILF, inferior longitudinal fasciculus; IQ, intelligence quotient.
  2. Scanning centre, age, and full scale IQ, were all included as covariates.
  3. aBayes factors (>0.33) indicate data sensitivity was insufficient to draw conclusions from.
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