Table 1 Relative risksa (with their 95% confidence intervals) of depression and fatigue within MZ, DZss and DZos twin pairs

From: A continuum of genetic liability for minor and major depression

Proband−co-twin

Aged

TE

 

MZ (643 pairs)

DZ ss (336 pairs)

DZ os F–M (241 pairs)

DZ os M–F (241 pairs)

MZ (1005 pairs)

DZ ss (804 pairs)

DZ os F–M (554 pairs)

DZ os M–F (554 pairs)

MiD−MiD

2.85 (1.62–5.00)

2.67 (1.09–6.51)

1.13 (0.27–4.66)

1.15 (0.29–4.51)

0.91 (0.37–2.23)

1.71 (0.79–3.72)

1.40 (0.49–3.98)

1.05 (0.38-2.85)

MiD−MD

7.32 (2.47–21.67)

2.04 (0.25–16.54)

4.24 (0.82–21.99)

4.02 (0.44–36.69)

1.64 (1.22–2.22)

1.17 (0.82–1.68)

1.06 (0.66–1.70)

1.40 (1.04–1.88)

MiD−MiD/MD

3.48 (2.19–5.54)

2.54 (1.15–5.61)

1.79 (0.66–4.83)

1.51 (0.50–4.53)

1.48 (1.14–1.92)

1.27 (0.95–1.69)

1.12 (0.75–1.66)

1.34 (1.04–1.71)

MD−MiD

5.45 (2.69–11.03)

2.22 (0.35–14.09)

3.53 (0.60–20.66)

3.44 (1.03–11.46)

1.17 (0.75–1.83)

1.06 (0.63–1.80)

1.72 (0.95–3.11)

0.99 (0.53–1.82)

MD−MD

6.02 (0.79–45.56)

2.16 (1.82–2.56)

1.46 (1.22–1.76)

1.16 (0.89–1.50)

1.17 (0.95–1.45)

MD−MiD/MD

5.53 (2.99–10.22)

1.76 (0.28–11.05)

2.79 (0.48–16.07)

3.01 (0.91–9.94)

1.94 (1.68–2.24)

1.39 (1.19–1.63)

1.26 (1.01–1.56)

1.14 (0.95–1.36)

MiD/MD−MiD

3.32 (2.04–5.42)

2.58 (1.12–5.94)

1.46 (0.45–4.75)

1.72 (0.64–4.60)

1.12 (0.73–1.73)

1.17 (0.72–1.91)

1.67 (0.94–2.97)

1.00 (0.57–1.76)

MiD/MD−MD

7.09 (2.50–20.05)

1.64 (0.20–13.42)

3.66 (0.70–19.08)

3.01 (0.33–27.85)

2.07 (1.75–2.45)

1.41 (1.18–1.69)

1.14 (0.89–1.46)

1.22 (1.01–1.48)

MiD/MD−MiD/MD

3.85 (2.54–5.84)

2.39 (1.12–5.06)

1.92 (0.78–4.76)

1.88 (0.79–4.48)

1.86 (1.62–2.14)

1.37 (1.18–1.60)

1.23 (1.00–1.52)

1.18 (1.00–1.39)

  1. Abbreviations: DZos, opposite-sex dizygotic; DZss, same-sex dizygotic; MD, major depression; MiD, minor depression; MZ, monozygotic; TE, Twin 89 cohort.
  2. aRelative risks and 95% confidence intervals were calculated with respect to non-depressed or non-fatigued status in twin 1. Same-sex twin pair tables were made symmetrical by averaging over using twin 1 or twin 2 as the proband.