Figure 1 | The Pharmacogenomics Journal

Figure 1

From: Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice

Figure 1

(a) Hepatic human APOA-I mRNA and plasma ApoA-I levels of individual ApoA-I transgenic mice treated with either a control or a fenofibrate-containing diet. (b) FPLC profiles of total cholesterol of ApoA-I transgenic mice fed a diet containing fenofibrate (FF) or without fenofibrate (control). (c and d) Fractionation of the plasma of ApoA-I transgenic mice fed the control (c) or fenofibrate-containing diet (d) by density gradient ultracentrifugation and analysis of the fractions by sodium dodecyl sulfate (SDS)-PAGE. The densities of the fractions are indicated at the top of the figures. (e and f) Electron microscopy pictures of the HDL fractions of ApoA-I transgenic mice fed the control (e) or fenofibrate-containing diets (f). The photomicrographs were taken at × 750 000 magnification and enlarged thrice. (g and h) Two-dimensional gel electrophoresis of plasma of the control (g) or the fenofibrate (h)-containing diets.

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